Publications

2023

CARVALHO, B. G. et al. Gelatin methacryloyl granular scaffolds for localized mRNA delivery. Aggregate, n. October, p. 1–15, 2023.

BIANCHI, J. R. DE O.; DE LA TORRE, L. G.; COSTA, A. L. R. Droplet-Based Microfluidics as a Platform to Design Food-Grade Delivery Systems Based on the Entrapped Compound Type. Foods, v. 12, n. 18, p. 3385, 2023.

WELTER, R. A. et al. Biodiesel Production by Heterogeneous Catalysis and Eco-friendly Routes. ChemBioEng Reviews, v. 10, n. 2, p. 86–111, 2023.

2022

MOUGENOT MF, PEREIRA VS, COSTA ALR, LANCELLOTTI M, PORCIONATTO MA, DA SILVEIRA JC, DE LA TORRE LG. Biomimetic Nanovesicles—Sources, Design, Production Methods, and Applications. Pharmaceutics, v. 14, 2022.

SOYSAL U, AZEVEDO PN, BUREAU F, AUBRY A, CARVALHO MS, PESSOAL ACSN, DE LA TORRE LG, COUTURE O, TOURIN A, FINK M, TABELING P. Freeze-Dried Microfluidic Monodisperse Microbubbles as a New Generation of Ultrasound Contrast Agents. Ultrasound in Medicine & Biology. v.48, p. 1484-1495. 2022.

COSTA OMMM, FIRMINO PCOS, STRAPASSON GB, DE LA TORRE LG, MALFATTI-GASPERINI AA, JÚNIOR SA. One-step Production of Sterically Stabilized Anionic Nanoliposome Using Microfluidic Device. Journal of Oleo Science v. 71 (4), pp. 515-522, 2022.

WELTER RA, SANTANA HS, CARVALHO BG, MELANI N, OELGEMÖLLER M, DE LA TORRE LG, TARANTO OP. Droplet microfluidics for double lipase immobilisation using TiO2 and alginate microbeads. Journal of Industrial and Engineering Chemistry, v 110, pp 576-586, 2022.

ROSILENE A. WELTER, HARRSON SANTANA, LUCIMARA G. DE LA TORRE,MARK ROBERTSON,OSVALDIR PEREIRA TARANTO, AND MICHAEL OELGEMÖLLER. Methyl Oleate Synthesis by TiO2 Photocatalytic Esterification of Oleic Acid: Optimisation by Response Surface Quadratic Methodology, Reaction Kinetics and Thermodynamics.

AMARAL JVM, DE LA TORRE LG, VIANNA SSV. Enhancement of the vorticity based on side feeding in a microdevice. Microfluidics and Nanofluidics (2022) 26:35.

EŞ I, MALFATTI-GASPERINI AA, DE LA TORRE LG. The diffusion-driven microfluidic process to manufacture lipid-based nanotherapeutics with stealth properties for siRNA delivery, Colloids and Surfaces B: Biointerfaces, 2022.

COSTA ALR, Willerth SM, de la Torre LG, HAN SW. Trends in hydrogel-based encapsulation technologies for advanced cell therapies applied to limb ischemia. Materials Today Bio 13 (2022) 10022.

CARVALHO BG, CECCATO BT, SANG SW, MICHELON M, DE LA TORRE LG. Advanced Microfluidic Technologies for Lipid Nano-Microsystems from Synthesis to Biological Application. Pharmaceutics, vol 14, issue 1.

OLIVEIRA AF, BASTOS RG, DE LA TORRE LG. Double T-junction microfluidic and conventional dripping systems for Bacillus subtilis immobilization in calcium alginate microparticles for lipase production. Enzyme and Microbial Technology 154,109976, 2022.

CARVALHO BG, GARCIA BBM, MALFATTI-GASPERINI AA, HAN SW, DE LA TORRE LG. Hybrid polymer/lipid vesicle synthesis: Association between cationic liposomes and lipoplexes with chondroitin sulfate. Colloids and Surfaces B: Biointerfaces 210, 112233, 2022.

2021

CARVALHO BG, VIT FF, CARVALHO HF, HAN SW, DE LA TORRE LG. Layer-by-Layer Biomimetic Microgels for 3D Cell Culture and Nonviral Gene Delivery. BIOMACROMOLECULES, 2021

FIRMINO PCOS, VIANNA SSV, DA COSTA OMMM, MALFATTI-GASPERINI AA, GOBBI AL, LIMA RS, DE LA TORRE LG. 3D micromixer for nanoliposome synthesis: a promising advance in high mass productivity. Lab on a Chip, Issue 15, 2021.

CINEL VDP, TAKETA TB, CARVALHO BG, DE LA TORRE LG, DE MELLO LR, DA SILVA ER, HAN SW. Microfluidic encapsulation of nanoparticles in alginate microgels gelled via competitive ligand exchange crosslinking. Biopolymers. 2021; e23432.

VIT FF, NUNES R, TZU WY, PRADO MCS, GODOI N, FUJIWARA E, CARVALHO HF, DE LA TORRE LG. A modular, reversible sealing, and reusable microfluidic device for drug screening. ANALYTICA CHIMICA ACTA v. 1185 , p. 339068. 2021.

AICH, A. ; LAMARRE, Y. ; SACOMANI, D. P. ; KASHIMA, S. ; COVAS, D. T. ; DE LA TORRE, L.G. . Microfluidics in Sickle Cell Disease Research: State of the Art and a Perspective Beyond the Flow Problem. FRONTIERS IN MOLECULAR BIOSCIENCES, v. 7, p. 1-17, 2021.

CARVALHO, BRUNA GREGATTI ; TAKETA, THIAGO BEZERRA ; GARCIA, BIANCA BONETTO MORENO ; HAN, SANG WON ; DE LA TORRE, LUCIMARA GAZIOLA . Hybrid microgels produced via droplet microfluidics for sustainable delivery of hydrophobic and hydrophilic model nanocarriers. Materials Science & Engineering C-Materials for Biological Applications, v. 118, p. 111467, 2021.

2020

CARVALHO BG, VIT FF, CARVALHO HF, HAN SW, DE LA TORRE LG. Recent advances in co-delivery nanosystems for synergistic action in cancer treatment. Journal of Materials Chemistry B, v. 1, p. 1-30, 2020

2019

Soares, M. C., Vit, F. F., Suzuki C. K., de la Torre, L. G., & Fujiwara E. (2019). Perfusion Microfermentor Integrated into a Fiber Optic Quasi-Elastic Light Scattering Sensor for Fast Screening of Microbial Growth Parameters. Sensors, 19(11), 2493.

Michelon, M., Huang, Y., de la Torre, L. G., Weitz, D. A., & Cunha, R. L. (2019). Single-step microfluidic production of W/O/W double emulsions as templates for β-carotene-loaded giant liposomes formation. Chemical Engineering Journal, 366, 27-32.

Perli, G., Pessoa, A. C., Balbino, T. A., & Lucimara, G. (2019). Ionic strength for tailoring the synthesis of monomodal stealth cationic liposomes in microfluidic devices. Colloids and Surfaces B: Biointerfaces.

Oliveira, A. F., Bastos, R. G., & Lucimara, G. (2019). Bacillus subtilis immobilization in alginate microfluidic-based microparticles aiming to improve lipase productivity. Biochemical Engineering Journal, 143, 110-120.

Vit, F. F., Oliveira, A. F., Rodríguez, D. A. O., de Carvalho, H. F., Lancellotti, M., & de la Torre, L. G. (2019). Perfusion microbioreactor system with permeable membranes to monitor bacterial growth. Journal of Chemical Technology & Biotechnology, 94(3), 712-720.

2018

Eş, I., Ok, M. T., Puentes-Martinez, X. E., de Toledo, M. A. S., de Pinho Favaro, M. T., Cavalcanti, L. P., … & de la Torre, L. G. (2018). Evaluation of siRNA and Cationic Liposomes Complexes as a Model for in vitro siRNA Delivery to Cancer Cells. Colloids and Surfaces A: Physicochemical and Engineering Aspects.

Soares, M. C., Mendes, B. F., Gomes, M. K., Bataglioli, R. A., Schenkel, E. A., Vit, F. F., … & Suzuki, C. K. (2018). Optical Fiber Sensor as an Alternative for Colorimetric Image Processing for the Assessment of Dye Concentration. In 2018 SBFoton International Optics and Photonics Conference (SBFoton IOPC) (pp. 1-5). IEEE.

Vitor, M. T., Sart, S., Barizien, A., De La Torre, L. G., & Baroud, C. N. (2018). Tracking the evolution of transiently transfected individual cells in a microfluidic platform. Scientific reports, 8(1), 1225.

Lucimara, G., Sipoli, C. C., Oliveira, A. F., Eş, I., Pessoa, A. C., Vitor, M. T., … & Naves, T. F. (2018). Biopolymers for gene delivery applications. In Biopolymer-Based Composites (pp. 289-323).

2017

Gómez-Mascaraque, L. G., Sipoli, C. C., de La Torre, L. G., & López-Rubio, A. (2017). A step forward towards the design of a continuous process to produce hybrid liposome/protein microcapsules. Journal of Food Engineering, 214, 175-181.

Gómez-Mascaraque, L. G., Sipoli, C. C., de La Torre, L. G., & López-Rubio, A. (2017). Microencapsulation structures based on protein-coated liposomes obtained through electrospraying for the stabilization and improved bioaccessibility of curcumin. Food chemistry, 233, 343-350.

Vitor, M. T., Bergami-Santos, P. C., Zômpero, R. H. F., Cruz, K. S. P., Pinho, M. P., Barbuto, J. A. M., & de la Torre, L. G. (2017). Cationic liposomes produced via ethanol injection method for dendritic cell therapy. Journal of liposome research, 27(4), 249-263.

Michelon, M., Oliveira, D. R. B., de Figueiredo Furtado, G., de la Torre, L. G., & Cunha, R. L. (2017). High-throughput continuous production of liposomes using hydrodynamic flow-focusing microfluidic devices. Colloids and Surfaces B: Biointerfaces, 156, 349-357.

Balbino, T. A., Serafin, J. M., Radaic, A., de Jesus, M. B., & Lucimara, G. (2017). Integrated microfluidic devices for the synthesis of nanoscale liposomes and lipoplexes. Colloids and Surfaces B: Biointerfaces, 152, 406-413.

Shiroma, L. S., Oliveira, A. F., Lobo-Júnior, E. O., Coltro, W. K., Gobbi, A. L., Lucimara, G., & Lima, R. S. (2017). High adhesion strength and hybrid irreversible/reversible full-PDMS microfluidic chips. Analytica chimica acta, 951, 116-123.

Alves, R. F., Favaro, M. T., Balbino, T. A., de Toledo, M. A., Lucimara, G., & Azzoni, A. R. (2017). Recombinant protein-based nanocarriers and their association with cationic liposomes: Characterization and in vitro evaluation. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 513, 1-10.

Pessoa, A. C., Sipoli, C. C., & Lucimara, G. (2017). Effects of diffusion and mixing pattern on microfluidic-assisted synthesis of chitosan/ATP nanoparticles. Lab on a Chip, 17(13), 2281-2293.

2016

Oliveira, A. F., Pessoa, A. C., Bastos, R. G., & de la Torre, L. G. (2016). Microfluidic tools toward industrial biotechnology. Biotechnology progress, 32(6), 1372-1389.

Balbino, T. A., Serafin, J. M., Malfatti-Gasperini, A. A., de Oliveira, C. L., Cavalcanti, L. P., de Jesus, M. B., & de La Torre, L. G. (2016). Microfluidic assembly of pDNA/Cationic liposome lipoplexes with high pDNA loading for gene delivery. Langmuir, 32(7), 1799-1807.

Oliveira, A. F., Pelegati, V. B., Carvalho, H. F., Cesar, C. L., Bastos, R. G., & De la Torre, L. G. (2016). Cultivation of yeast in diffusion-based microfluidic device. Biochemical engineering journal, 105, 288-295.

Sipoli, C. C., Radaic, A., Santana, N., de Jesus, M. B., & de la Torre, L. G. (2015). Chitosan nanoparticles produced with the gradual temperature decrease technique for sustained gene delivery. Biochemical engineering journal, 103, 114-121.

2015

Balbino, T. A., Correa, G. S., Favaro, M. T., Toledo, M. A., Azzoni, A. R., & Lucimara, G. (2015). Physicochemical and in vitro evaluation of cationic liposome, hyaluronic acid and plasmid DNA as pseudo-ternary complexes for gene delivery. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 484, 262-270.

Gasperini, A. A., Puentes-Martinez, X. E., Balbino, T. A., de Paula Rigoletto, T., de Sá Cavalcanti Corrêa, G., Cassago, A., … & Cavalcanti, L. P. (2015). Association between cationic liposomes and low molecular weight hyaluronic acid. Langmuir, 31(11), 3308-3317.

Sipoli, C. C., Santana, N., Shimojo, A. A. M., Azzoni, A., & de la Torre, L. G. (2015). Scalable production of highly concentrated chitosan/TPP nanoparticles in different pHs and evaluation of the in vitro transfection efficiency. Biochemical engineering journal, 94, 65-73.

2014

M.T.P. Favaro, M.A.S. de Toledo, R.F. Alves, C.A. Santos, L.L. Beloti, R. Janissen, L.G. de la Torre, A.P. Souza, A.R. Azzoni. Development of a non-viral gene delivery vector based on the dynein light chain Rp3 and the TAT peptide, Journal of Biotechnology, Volume 173, 2014.

De La Torre, L. G., Balbino, T. A., Sipoli, C. C., Vitor, M. T., & Oliveira, A. F. (2014). Trends on microfluidic liposome production through hydrodynamic flow-focusing and microdroplet techniques for gene delivery applications. Advances in Liposomes Research. New York: Nova Science Publishers, 63-96.

2013

Balbino, T. A., Azzoni, A. R., & de La Torre, L. G. (2013). Microfluidic devices for continuous production of pDNA/cationic liposome complexes for gene delivery and vaccine therapy. Colloids and Surfaces B: Biointerfaces, 111, 203-210.

Vitor, M. T., Bergami-Santos, P. C., Barbuto, J. A., & Torre, L. G. (2013). Cationic liposomes as non-viral vector for RNA delivery in cancer immunotherapy. Recent patents on drug delivery & formulation, 7(2), 99-110.

Balbino, T. A., Aoki, N. T., Gasperini, A. A., Oliveira, C. L., Azzoni, A. R., Cavalcanti, L. P., & Lucimara, G. (2013). Continuous flow production of cationic liposomes at high lipid concentration in microfluidic devices for gene delivery applications. Chemical engineering journal, 226, 423-433.

2012

Balbino, T. A., Gasperini, A. A., Oliveira, C. L., Azzoni, A. R., Cavalcanti, L. P., & de La Torre, L. G. (2012). Correlation of the physicochemical and structural properties of pDNA/cationic liposome complexes with their in vitro transfection. Langmuir, 28(31), 11535-11545.

2011

de Paula Rigoletto, T., Zaniquelli, M. E. D., Santana, M. H. A., & de la Torre, L. G. (2011). Surface miscibility of EPC/DOTAP/DOPE in binary and ternary mixed monolayers. Colloids and Surfaces B: Biointerfaces, 83(2), 260-269.